Hepatitis

GenMark is committed to expanding its menu of multiplex molecular panels to address a wide variety of clinical needs in the area of hepatitis. The following information is provided as an educational resource only.

WHAT IS HEPATITIS C?
Hepatitis C is a liver infection caused by the hepatitis C virus (HCV) that can lead to severe liver disease. Roughly 20% of people infected with HCV clear the virus on their own without treatment, however most people develop a lifelong, or chronic HCV infection.1 Many people infected with HCV are asymptomatic for decades and when symptoms do present, it often indicates advanced liver disease.1 Symptoms of HCV include fever, fatigue, lack of appetite, nausea, vomiting, joint pain, and yellowing of the skin and eyes. Chronic HCV infection can lead to increased risk of liver cirrhosis, hepatocellular carcinoma, liver failure, and related morbidities.2

HOW PREVALENT IS HCV?
HCV is the most common chronic blood-borne infection in the United States, and nearly four million people are chronically infected.2 It is estimated that 130 million people worldwide are chronically infected with HCV.3 Due to the asymptomatic nature of infection and slow disease progression, 45% to 85% of infected patients are unaware of their HCV infection until they present with liver disease.2

VIEW HCV GENOTYPING PANEL ON ePLEX*

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References:
1. Centers for Disease Control and Prevention. Hepatitis C General Information, 2015 update. http://www.cdc.gov/hepatitis/
2. Smith, B.D. et al. (2012). Recommendations for the Identification of Chronic Hepatitis C Virus Infection Among Persons Born During 1945–1965. MMWR Recommendations and Reports, 61(4), 1–32.
3. European Centre for Disease Prevention and Control. Hepatitis C. http://ecdc.europa.eu/en/healthtopics/hepatitis_C/Pages/index.aspx

*Product in development. Not available for sale in the US. Specifications subject to change.