Blood Culture Identification (BCID) Panels

GenMark’s ePlex Blood Culture Identification (BCID) panels provide the broadest inclusivity of pathogens that cause sepsis and their resistance genes. This and the ease of use of the ePlex system makes ePlex BCID panels the only tests for rapid, routine blood culture identification.

The Sepsis Challenge: Since traditional diagnostic methods can take days to identify the causative agents of sepsis, 20-30% of patients receive ineffective initial antibiotic therapy^[1], and it is estimated that for every hour effective antibiotics are delayed, the mortality rate for sepsis increases up to 7.6%^[2].  Therefore early identification of the cause of sepsis is critical to ensuring better patient outcomes.

The ePlex BCID Solution:  Bacterial and fungal organisms responsible for greater than 95%^[3] of  blood stream infections and their associated resistance genes can be identified in about 1.5 hours after initial bottle culture, saving critical time to diagnosis.

ePlex BCID saves days compared to conventional methods and is designed to:

• Decrease time to appropriate antimicrobial treatment
• Reduce hospital length of stay and overall costs
• Improve antibiotic stewardship and infection control
• Improve patient outcomes

Choose the appropriate ePlex BCID Panel based on your Gram stain result:

Gram-Positive Organisms	Gram-Negative Organisms	Fungal Organisms
Bacillus cereus group	Acinetobacter baumannii	Candida albicans
Bacillus subtilis group	Bacteroides fragilis	Candida auris
Corynebacterium	Citrobacter	Candida dubliniensis
Cutibacterium acnes	Cronobacter sakazakii	Candida famata
(Propionibacterium acnes)	Enterobacter (non-cloacae complex)	Candida glabrata
Enterococcus	Enterobacter cloacae complex	Candida guilliermondii
Enterococcus faecalis	Escherichia coli	Candida kefyr
Enterococcus faecium	Fusobacterium nucleatum	Candida krusei
Lactobacillus	Fusobacterium necrophorum	Candida lusitaniae
Listeria	Haemophilus influenzae	Candida parapsilosis
Listeria monocytogenes	Klebsiella oxytoca	Candida tropicalis
Micrococcus	Klebsiella pneumoniae	Cryptococcus gattii
Staphylococcus	Morganella morganii	Cryptococcus neoformans
Staphylococcus aureus	Neisseria meningitides	Fusarium
Staphylococcus epidermidis	Proteus	Rhodotorula
Staphylococcus lugdunensis	Proteus mirabilis
Streptococcus	Pseudomonas aeruginosa
Streptococcus agalactiae (GBS)	Salmonella
Streptococcus anginosus group	Serratia
Streptococcus pneumoniae	Serratia marcescens
Streptococcus pyogenes (GAS)	Stenotrophomonas maltophilia
Resistance Genes	Resistance Genes
mecA	CTX-M
mecC	KPC
vanA	NDM
vanB	VIM
Pan Targets	IMP
Pan Gram-Negative	OXA
Pan Candida	Pan Targets
	Pan Gram-Positive
	Pan Candida

Streamlined Workflow for Accelerated Results

Sample to result in ~1.5 hours <2 minutes of hands-on time

1. Load Sample

2. Load Cartridge

3. Report Results

[1] IDSA: Better Tests Better Care, The Promise of Next Generation Diagnostics.
[2] Kumar, et. al., Crit Care Med 2006 Vol. 34, No. 6
[3] Detection rate is based on panel inclusivity compared to the GenMark prospective clinical trial database and an additional clinical data set (Potula, et. al., (2015) MLO), and is not a sensitivity/performance claim.